Land mark events and heroes of CRISPR Genomic Resources and gate ways of their utilization Knock down vs knock out of genes in trait modification Recent developments in CRISPR variants Potential application of CRISPR in improving plant traits CRISPR-Cas technology as next generation breeding tool Improving fungal disease resistance in plants through Genome Editing Genome Editing in Insect/Nematodes Genome editing for human health management Genome editing in crops for nutritional quality Genome editing in improving abiotic stress tolerance in crops Regulation of GE products in India Regulation of genome edited crops- Global Scenario